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Thursday 01 June 2006

[A case of MALT lymphoma of the liver treated by RFA and Rituximab]

By: Hamada M, Tanaka Y, Kobayashi Y, Takeshita E, Joko K.

Nippon Shokakibyo Gakkai Zasshi 2006 Jun;103(6):655-60

A 69 years old man was admitted to our hospital for further examinations of the liver tumor October, 2003. No underlying liver disease was found. Two tumors in the liver, 2cm in diameter respectively, were detected by abdominal ultrasonography and MRI scan. Ultrasonogram-guided needle biopsy from the liver tumor showed diffuse infiltration of CD20 positive, small lymphocytes. A distinct single band demonstrating clonal JH gene rearrangement was detected by southern blot analysis using tissues by needle biopsy. Thus, the patient was diagnosed with primary hepatic MALT lymphoma in the normal liver. These tumors were treated with percutaneus radiofrequency ablation (RFA), followed by Rituximab administration. No relapse has been noted until September, 2005.

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