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Friday 01 August 2003

Regression of cutaneous intravascular lymphoma with rituximab.

By: Han K, Haley JC, Carlson K, Pinter-Brown L, Soriano T.

Cutis 2003 Aug;72(2):137-40

Intravascular lymphoma, also known as malignant angioendotheliomatosis or angiotropic lymphoma, is a rare non-Hodgkin lymphoma that is usually fatal. It often presents with cutaneous and/or nervous system involvement, but the disease can involve any organ system. Clinical symptoms result from the occlusion of small vessels by tumor cells and fibrin. We present a case of cutaneous intravascular lymphoma successfully treated with rituximab, a recombinant antibody to CD20 antigen found on B lymphocytes.

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